Medical University of South Carolina
Welcome MUSC Visitors

The Mills House Wyndham Grand Hotel
115 Meeting Street
Charleston, SC 29401

Special MUSC rates from $139 - $299, seasonally
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Rates subject to availability.




Originally opened in 1853 and completely restored in 2014, our landmark hotel combines historic charm with contemporary luxury to provide the quintessential Charleston experience. Located in the very heart of the Historic District, the Mills house Wyndham Grand Hotel places you just steps away from the fine dining, boutique shopping and historical attractions that have placed Charleston among the top destinations in the world.

The hotel boasts award winning dining, a new fitness center, concierge service and an outdoor pool. These amenities, along with the completely renovated guest room and a total commitment to service, make the Mills House the first choice for visitors seeking an authentic Charleston experience.

The Mills House is honored by AAA's "Four Diamond" designation.

We invite you to step through our landmark arches, back to the charm of 19th century Charleston. Experience the Legend. The Mills House Hotel.



Amenities include:

  • 216 non-smoking guest rooms and suites
  • Handicapped accessible
  • Historical setting
  • Complimentary wireless internet access in guest rooms and throughout hotel
  • Fitness center
  • Outdoor seasonal pool
  • 24-hour business center
  • Barbadoes Dining Room serving breakfast, lunch and dinner
  • First Shot Lounge serving coffee and cocktails
  • Fountain courtyard for dining and cocktails
  • Daily concierge service
  • Wyndham Rewards points
  • Languages spoken: English